Protein C & S are deficient in Congenital cause, treatment with oral anticoagulant, liver disease. Factor V Leiden mutation is associated with thrombotic tendency.
It is helpful in determining the cause of anaemia either due to impaired RBC production or increased destruction in peripheral blood.
RET- He measures the haemoglobin content of reticulocytes and an early marker for iron deficient erythropoiesis (because of the 4 days life span of reticulocytes).
IRF (Immature Reticulocyte Fraction) is an early marker for evaluating the regeneration of erythropoiesis.
Immature Granulocyte (IG) count is a useful early marker of infection or inflammation. It is an early and rapid discrimination of bacterial from viral infections.
IPF - Immature Platelet Fraction indicates thrombopoietic activity. Elevated IPF indicates bone marrow regeneration in case of peripheral platelet consumption / destruction.
